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1.
Comput Ind Eng ; 162: 107668, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1415274

ABSTRACT

Municipal solid waste (MSW) directly impacts community health and environmental degradation; therefore, the management of MSW is crucial. Medical waste is a specific type of MSW which is generally divided into two categories: infectious and non-infectious. Wastes generated by coronavirus disease 2019 (COVID-19) are classified among infectious medical wastes; moreover, these wastes are hazardous because they threaten the environment and living organisms if they are not appropriately managed. This paper develops a bi-objective mixed-integer linear programming model for medical waste management during the COVID-19 outbreak. The proposed model minimizes the total costs and risks, simultaneously, of the population's exposure to pollution. This paper considers some realistic assumptions for the first time, including location-routing problem, time window-based green vehicle routing problem, vehicles scheduling, vehicles failure, split delivery, population risk, and load-dependent fuel consumption to manage both infectious and non-infectious medical waste. We apply a fuzzy goal programming approach for solving the proposed bi-objective model, and the efficiency of the proposed model and solution approach is assessed using data related to 13 nodes of medical waste production in a location west of Tehran.

2.
Ann Oper Res ; : 1-34, 2021 Jun 03.
Article in English | MEDLINE | ID: covidwho-1252145

ABSTRACT

Developing countries scramble to contain and mitigate the spread of coronavirus disease 2019 (COVID-19), and world leaders demand equitable distribution of vaccines to trigger economic recovery. Although numerous strategies, including education, quarantine, and immunization, have been used to control COVID-19, the best method to curb this disease is vaccination. Due to the high demand for COVID 19 vaccine, developing countries must carefully identify and prioritize vulnerable populations and rationalize the vaccine allocation process. This study presents a mixed-integer linear programming model for equitable COVID-19 vaccine distribution in developing countries. Vaccines are grouped into cold, very cold, and ultra-cold categories where specific refrigeration is required for their storage and distribution. The possibility of storage for future periods, facing a shortage, budgetary considerations, manufacturer selection, order allocation, time-dependent capacities, and grouping of the heterogeneous population are among the practical assumptions in the proposed approach. Real-world data is used to demonstrate the efficiency and effectiveness of the mathematical programming approach proposed in this study.

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